After 3 weeks trials with an iCaps capsule polisher,…EXHIBITION | Achema - Frankfurt, Germany - 22-26 August 2022
Visit us at the Achema on August 22-26th, the…Towards real-time release of pharmaceutical tablets: 100% in-line control via near-infrared spatially resolved spectroscopy and 3D microwave resonance technology
Highlights • This technique reduces the uncertainty of sample…OEB 3 - 100% Individual Mass Measurement of Capsules and Tablets CW-150
1. Introduction The new CW-150 checkweigher from Pharma Technology was launched…Case study iSpray – External lubrication system
The Challenge: Punch sticking, hardness stability, and high ejection…PHARMA TECHNOLOGY reveals its growth strategy 2025
Pharma Technology, with more than 25 years of experience…
In the scope of 100% in-line quality control and real-time release of pharmaceutical tablets, the authors present a flexible inspection module for in-line tablet analysis with integrated multipoint near-infrared (NIR) spectroscopy and 3D microwave resonance technology (3D MRT). Via an industrial case study on Diclofenac Sodium tablets, the abilities of this versatile process analytical technology (PAT) tool are presented. It is demonstrated that the combination of Diclofenac concentration prediction via NIR spectroscopy and mass prediction via 3D MRT allow to estimate the dosage of each individual tablet. Single sample repetition tests were performed on 5 tablets, measured 10 times on three different days. A high accuracy and precision of prediction was shown, with an average standard deviation below 0.5 mg. The inspection run demonstrated the added value of such inspection and sorting strategies based on the calculated dosage of individual tablets.