Another Success Story with Metrics Contract Services US
Metrics Contract Services, a full-service global contract development and…
Tackling OSD development challenges with CUB-X
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SMEPAC test passed with HC dedusters and metal checks
Dedusters and Metal Checks Standardized Measurement of Equipment Particulate…
New partner for Q-Control Division
We are delighted to enter into a new collaboration…
Digital equipment 's showcase
As we unfortunately cannot participate in events & exhibitions…
Success Story | Achieve extra polishing with food supplements
“Our challenge is to get a clean, shiny capsule,…
In the scope of 100% in-line quality control and real-time release of pharmaceutical tablets, the authors present a flexible inspection module for in-line tablet analysis with integrated multipoint near-infrared (NIR) spectroscopy and 3D microwave resonance technology (3D MRT). Via an industrial case study on Diclofenac Sodium tablets, the abilities of this versatile process analytical technology (PAT) tool are presented. It is demonstrated that the combination of Diclofenac concentration prediction via NIR spectroscopy and mass prediction via 3D MRT allow to estimate the dosage of each individual tablet. Single sample repetition tests were performed on 5 tablets, measured 10 times on three different days. A high accuracy and precision of prediction was shown, with an average standard deviation below 0.5 mg. The inspection run demonstrated the added value of such inspection and sorting strategies based on the calculated dosage of individual tablets.
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