The surplus of lubricant is eliminated by vacuum directly on the spray nozzle, then collected in a removable bin.
iSpray has several innovatively designed features, including a compact double-sided nozzle that fits most rotary table presses for optimal coverage of most tool sizes, and a backup line with a pressure sensor built into each nozzle, which automated switching between lines that, in doing so, helps avoid costly interruptions due to a potential blockage.

For recipe storage, the system is equipped with a touch screen HMI with audit trail recording, compliant with FDA.
iSpray helps reduce the amount of dry lubricant in the compression blend, while applying an optimized amount of lubricant to the upper punch face, die wall, and lower punch face.

Excess lubricant is directly vacuumed, next to the nozzle.  This allows consistent amounts of lubricant to be applied on tablets throughout a lengthy batch and from one batch to another. The amount applied can therefore be validated.

For existing hygroscopic or effervescent formulations the system helps reduce the die wall friction at the ejection stage, and the lower punch face friction at the take-off stage. In addition, it helps prevent logo picking or stickiness issues. This provides the added benefit of reducing wear on and extending the life of tooling and ejection cams.

For new formulations, the system helps eliminate the use of dry lubricant in the blend, thus eliminating an extra step in the manufacturing process and greatly enhancing the solubility of the tablet. This solubility enhancement has been in great demand for new drugs that often have poorly soluble APIs (especially with biotech drugs). The minimal quantity of lubricant sprayed externally onto tablets can be accurately measured and validated to meet the requirements for the formulations under US Pharmacopeia.

 

 

WHITE PAPER | iSpray
For effective tablet lubrication
in the pharmaceutical industry

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