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The CUB-X is an innovative and versatile tablet inspection system, which can be used for OSD product & process development, as well as for IPC sample analysis and full batch inspection & sorting.
It is equipped with novel spectroscopy and laser technologies allowing for high-speed highly accurate non-destructive measurement of tablet thickness, API’s mass fraction and moisture content.
The CUB-X can measure tablet mass fraction for multiple ingredients – including moisture – at speeds up to 20.000 tablets/h using NIR-SRS spectroscopy, while tablets can be sampled at speeds up to 400 tablets/h for measurement of mass, thickness, diameter/length and hardness. This allows sampled tablets to be analyzed for porosity, dosage, and content uniformity, while all tablets are analyzed for API mass fraction.
EMBEDDED TECHNOLOGIES
A laser line-scanning sensor profiles each tablet, while passing under the sensor, measuring its thickness with a precision of 50 µm. The tablet laser profiler also verifies the correct position and orientation of the tablet on the conveyor belt before it passes under the NIR-SRS sensor.
Each tablet is inspected by the multipoint NIR-SRS (Near-Infra-Red Spatially Resolved Spectroscopy) probe at a high frame rate, allowing multiple spectral acquisitions per tablet. An accurate prediction of one or multiple ingredients’ mass fraction – including water – is then done by chemometric modelling. The SRS technology allows to cover a larger tablet surface and a deeper measurement penetration compared to single-point NIR reflection techniques, resulting in more accurate prediction of the CQA’s.
Samples can be sent to an embedded 4-parameter tablet tester at a rate of up to 400 tablets/h, measuring tablet mass, thickness, diameter/length, and hardness. The high sampling rate is achieved thanks to a purpose-designed sampling gate, which feeds tablets one by one directly to the measurement instruments
Maximum inspection speed | 20.000 tablets/h |
Maximum sampling rate | 400 tablets/h |
Minimum product width | 4 mm |
Maximum product width | 24 mm |
Minimum product height | 3 mm |
Maximum product height | 10 mm |
Thickness measurement accuracy | ± 0,05 mm |
Mass accuracy | ± 1 mg in stable environment |
Hardness measurement accuracy | ± 2 N (4-400 N range) |
Length measurement accuracy | ± 0,1 mm |
Air extraction | Integrated Hepa filter H13 |
Requested compressed air | Min 500 L/min - Min. 6 bar |
Nosie level | ≤70 dB (A) |
Power supply | 380 V 3ph + N + PE |
Frequency | 50 Hz / 60 Hz |
Polymer contact parts | FDA approved |